GP000100: MUC1(126-149)-STn(130,131) – www.tbsmovers.com

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GP000100: MUC1(126-149)-STn(130,131)

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Description

GP000100: MUC1(126-149)-STn(130,131)C133H209N33O58 3198. 27 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Pro126 Gly149; UniProt position 126 149, aa length 24) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Sialyl Tn or STn (Neu5Ac2 6GalNAc O Ser) at Ser130 and Neu5Ac2 6GalNAc O Thr at Thr131. The C terminus is carboxylic acid. MUC1(126 149) STn(130,131) Mucin1; Synthetic MUC 1 (di STn) glycopeptide

C24H27NO9 / 473

61 / An α-D-N-acetylgalactosamine (GalNAcα) ligand on a threonine residue (Tn antigen

Vitamin D3 (26

/ MUC1(126-149-Cys)-STn(131

Fmoc-Asn(beta-D-Glc)-OH (Peracetate)

α-D-Man-Et-SH

73 / / Vitamin E-d3 (R

an α1-2-linked glucose disaccharide

The installed glycan is a maltose (Glcα1-4Glc) disaccharide

β-D-GalNAc(Ac)3-Butyl-COOH

and biological activity

This compound provides a lactose (Galβ1-4Glc) building block for glycoconjugate synthesis and the construction of probes for galactose-recognizing proteins

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